Conference Committee

Gary Perdew
Conference Chair
Endowed Professor of Molecular Toxicology at The Pennsylvania State University, Director of the Center for Molecular Toxicology and Carcinogenesis. He has worked over the past 30 years on the biochemistry of the Ah receptor (AHR) pathway, mechanisms of AHR-mediated gene regulation, identification of endogenous, dietary, and bacterial AHR ligands and the biology of the AHR in normal and cancerous epithelium.
Andrew Patterson
Conference Co-Chair
Tombros Endowed Chair and Professor of Molecular Toxicology at The Pennsylvania State University, Scientific Director of Metabolomics. His laboratory studies the host-microbiome interaction and its perturbation by persistent environmental AHR ligands.

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Xavier Coumoul
Professor of Biochemistry and Toxicology (University Paris Descartes, PRES), has worked for many years on the molecular effects of environmental pollutants using several models (cells, invertebrates, mice) and clinical studies. He has focused his activity on the Aryl hydrocarbon Receptor, a transcriptional factor, which is activated by many xenobiotics. His research work is complementary to his teaching activities (Director of the Toxicology Master’s Degree Program) in which he implements innovative teaching approaches.
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Michael Denison
Ph.D., fellow ATS, Distinguished Professor Emeritus at the University of California. His research efforts have focused on the biochemical, molecular and toxicological mechanisms of action of the Ah receptor (AhR) and AhR signaling pathways, including identification and characterization of structurally diverse AhR ligands and ligand diversity in AhR signaling, analysis of the AhR structure-function, species-specific differences in the AhR and regulation of AhR-dependent gene expression.
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Charlotte Esser
Immunotoxicologist interested in the effect of AHR and its xenobiotic, dietary and endogenous ligands on immunity, in particular barrier immunity (skin and gut). She is a group leader at the IUF, Düsseldorf, Germany, and has published more than 50 original papers and reviews on these topics.
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Pedro Fernandez Salguero
Full professor for Biochemistry and Molecular Biology and coordinator of the catalogued research group « Molecular Biology of Cancer ». Teaching includes graduate and postgraduate disciplines on Cell Signaling in human disease, Mammalian transgenesis and Molecular Genetics. Research is currently devoted to understand de causal role of AhR in regulating pluripotency, reprogramming and differentiation using cellular systems, transgenic models for AhR, oncogenes and reprogramming genes and human biopsies from cancer patients.
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Paige Lawrence
PhD, Professor of Environmental Medicine and of Microbiology & Immunology; Director, Rochester Toxicology Program; Deputy Director Environmental Health Science Center. Delineating mechanisms by which environmental signals during different life stages regulate the immune system; discovering how environmental signals modulate epigenetic programming of the developing immune system, and the consequences of these changes on susceptibility to infectious, allergic, or autoimmune disease later in life.
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David Sherr
Since 1993, David Sherr’s laboratory has conducted research on how common environmental pollutants, such as dioxins, polycyclic aromatic hydrocarbons and PCBs, adversely affect the growth and behavior of several different types of normal and malignant cells. In previous work, the Sherr laboratory studied how environmental chemicals affect the development of the immune system. In specific, his laboratory demonstrated that aromatic hydrocarbons (generated by the combustion of any carbon source) compromise the function of bone marrow cells required for the development of antibody-forming cells.