Developing Medical Countermeasures To Treat the Acute and Chronic Effects of Ocular Chemical Toxicity

(A Trans-Agency Scientific Meeting)

Registration for this meeting closed January 31, 2020.

Target Audience:

  • Academic, industry and government researchers engaged in developing therapeutic approaches and medical countermeasures (MCMs) against ocular pathologies resulting from exposure to chemical toxicants
  • Government stakeholders and funding agencies 

Objectives of the Scientific Meeting:

  • Development of MCMs that mitigate acute and chronic corneal manifestations in response to ocular toxicants relies on the development of well-characterized experimental models with defined pathophysiology that allow for effective bridging to humans. Such models are also essential to demonstrate therapeutic efficacy.
  • This meeting will bring together subject matter experts from the civilian and military research communities to discuss the current state of the field, including potential therapeutic approaches and available models.
  • Attendees of the workshop will contribute to our understanding of pathologies and models available for studying toxic ocular injuries and their utility in the research and development of therapeutics. Most importantly, the workshop will address current knowledge gaps to identify possible refinements or new directions to advance MCM development.

Session Topics:

  • Acute and Chronic Wound Healing Responses to Corneal Toxicity
  • Mechanistic Basis of Corneal Pathophysiologies
  • Therapeutically Accessible Models of Corneal Toxic Injury
  • Therapeutic Approaches to Mitigate Corneal Pathophysiologies
  • Current Research & Development Perspectives and Resources for Researchers
  • Meeting Wrap Up 


  • Houmam Araj, Ph.D. – National Eye Institute (HHS/NIH/NEI)
  • Patrick McNutt, Ph.D. – U.S. Army Medical Research Institute for Chemical Defense (DoD/USAMRICD)
  • Dave Yeung, Ph.D. – National Institute of Allergy and Infectious Diseases (HHS/NIH/NIAID)



  • When

  • Tuesday, February 25, 2020 - Wednesday, February 26, 2020
    8:30 AM - 6:00 PM
    Eastern Time

  • Where

  • NIAID Conference Center
    5601 Fishers Lane
    Rockville, Maryland 20852

Additional Information

This trans-agency scientific meeting is sponsored by the Chemical Countermeasures Research Program (CCRP), a component of the broader civilian biodefense research effort within HHS and NIH.  The overarching goal of the CCRP is to integrate cutting edge research with the latest technological advances in science and medicine to enhance the nation’s medical response capabilities during public health emergencies involving the accidental or intentional release of Department of Homeland Security-identified chemical threat agents, which include various ocular toxicants. To learn more about the CCRP’s trans-NIH effort, see the recently published (Nov 2018) Report on Research Progress and Future Directions of the NIH Medical Research Program Directed Against Chemical Threats (pdf).

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