ENDOTEXT Series: Staying Current in Endocrinology "Gigantism"
Section: Pediatric Endocrinology
Gigantism refers to a condition characterized by extreme physical size and stature. By definition, this originates during infancy, childhood or adolescence, while epiphyseal growth plates remain open. Although often used to specifically denote growth hormone excess, the term gigantism is also applied to a number of non-hormonally mediated overgrowth conditions in children. All forms of gigantism are extremely rare, and have in common a complex pathophysiologic origin and extraordinary clinical manifestations. Although many aspects of overgrowth disorders remain to be elucidated, insights into the molecular genetic basis of several forms of gigantism have contributed greatly to our understanding of specific mediators of growth and cellular function. Both growth hormone hypersecretion and overgrowth syndromes will be reviewed in this chapter.
Erica A. Eugster, M.D. Professor of Pediatrics, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN Director, Section of Pediatric Endocrinology/Diabetology Riley Hospital for Children Indianapolis, IN
This continuing medical education program is intended for physicians, nurse practitioners, and other interested healthcare professionals.
This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education. The University of Mississippi School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to sponsor continuing medical education for physicians.
It is estimated that it will require 2 hour to review the text material in this continuing medical education program and answer the self-assessment questions. After completing the program, answer post test questions and evaluation questions through CVENT. A minimum of 70% of the questions must be answered correctly to receive credit. Upon successful completion of the post test and evaluation, you will be emailed a certificate of completion within 7 days. Contact us inquires regarding the content of this CME program should be addressed to: Brea Cole, Program Administrator - email@example.com
Windows: X86 or x64 (64-bit mode support for IE only) 1.6-gigahertz (GHz) or higher processor with 512-MB of RAM, sound card and speakers. Internet Explorer 7+, Google Chrome 12+, and Firefox 3.6+ Mac: a Mac running Mac OS 10.4.11+ (Browsers must be in 32-bit mode), an Intel Core Duo 1.83-gigahertz (GHz) or higher processor with 512-MB of RAM, sound capabilities, and Safari 5.1+, Google Chrome 16.0+. Internet Connection: A Cable or DSL internet connection (200 kbps+) is highly recommended for the best experience. A low speed modem connection (56k) can be used, but is not recommended and buffering is to be expected. Release date: September 18, 2013 Expiration date: August 31, 2015
Brea Cole, Continuing Education, University of Mississippi Medical Center
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