All sessions of the conference will take place in the Bayhill Conference Rooms


Agenda

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    • Thursday, January 11, 2018
    •  

      Registration

      5:00 PM  -  7:00 PM
      Conference Registration
    • Friday, January 12, 2018
    •  

      Clinical Session 1

      7:00 AM  -  5:00 PM
      Conference Registration
      7:00 AM  -  8:00 AM
      Breakfast
      8:00 AM  -  8:15 AM
      Welcome & Course Goals
      Clinical Session 1- Heme Biosynthesis & Acute Hepatic Porphyrias
      Co-Chairs: J.C Deybach, MD, PhD & E. Sardh, MD, PhD
      8:15 AM  -  9:00 AM
      Heme Biosynthesis & Degradation for Clinicians
      9:00 AM  -  9:45 AM
      Porphyria Genetics: Inheritance and Molecular Diagnosis
      10:00 AM  -  10:45 AM
      The Acute Hepatic Porphyrias (AHPs): Metabolic Defects, Pathophysiology & Clinical Manifestations
      10:45 AM  -  11:30 AM
      AHPs: Diagnosis and Current Management
      Speakers:
      11:30 AM  -  12:00 PM
      AIP Patient Interview
      12:00 PM  -  12:30 PM
      Expert Panel: Critical Issues to Resolve & Future Directions
      Moderators: J.C Deybach, MD, PhD & E. Sardh, MD, PhD
      Panelists include:
      12:30 PM  -  1:30 PM
      Lunch
       

      Clinical Session 2

      Clinical Session 2 - Porphyria Cutanea Tarda
      Co-Chairs: P. Wilson, MD & H. Puy, MD, PhD
      1:30 PM  -  2:15 PM
      Porphyria Cutanea Tarda: Metabolic Defect, Predisposing Factors, Pathophysiology & Treatment
      2:15 PM  -  2:45 PM
      PCT Patient Interview
      Speakers:
      2:45 PM  -  3:15 PM
      Expert Panel: Critical Issues to Resolve & Future Directions
      Moderators: P. Wilson, MD & H. Puy, MD, PhD
      Panelists include:
       

      Clinical Session 3

      Clinical Session 3 - The Erythropoietic Porphyrias
      Co-Chairs: E. Minder, MD & M. Poh-Fitzpatrick, MD
      3:30 PM  -  4:15 PM
      Congenital Erythropoietic Porphyria (CEP): Metabolic Defect, Pathophysiology & Treatments
      4:15 PM  -  4:45 PM
      CEP Patient Interview
      4:45 PM  -  5:30 PM
      Erythropoietic Protoporphyria (EPP) & X-Linked Protoporphyria (XLP): Metabolic Defects, Pathophysiol
      5:30 PM  -  6:00 PM
      EPP/XLP Patient Interview
      6:00 PM  -  6:30 PM
      Expert Panel: Critical Issues to Resolve & Future Directions
      Moderators: E. Minder, MD & M. Poh-Fitzpatrick, MD
      Panelists include:
      7:00 PM  -  8:00 PM
      Reception
      8:00 PM  -  10:30 PM
      Dinner
    • Saturday, January 13, 2018
    •  

      Research Session 1

      7:00 AM  -  5:00 PM
      Conference Registration
      7:00 AM  -  8:00 AM
      Breakfast- Talk Tables for Trainees with Senior Investigators
      Research Session 1 - Chemistry, Biology, and Genetics of Human Heme Biosynthesis
      Co-Chairs: R.J. Desnick, PhD, MD & B. Paw, MD, PhD
      8:00 AM  -  8:35 AM
      Regulation and Tissue Specific Expression of ALAS
      Speakers:
      8:35 AM  -  9:10 AM
      Structure and Assembly of ALAS
      Speakers:
      9:10 AM  -  9:45 AM
      Human ALAS1 and ALAS2 Catalysis
      Speakers:
      10:15 AM  -  10:50 AM
      ALAS2: Identification of an endogenous inhibitor
      Speakers:
      10:50 AM  -  11:20 AM
      Selected Abstract Talks 1 & 2
      11:20 AM  -  12:00 PM
      Expert Panel: Critical Issues to Resolve and Future Directions
      Moderators: R.J. Desnick, PhD, MD & B. Paw, MD, PhD
      Panelists include:
      12:00 PM  -  1:00 PM
      Lunch – Trainee Talk Tables with Expert Presenters
       

      Research Session 2

      Research Session 2- Porphyrins and Porphyrin Precursors in Health and Disease
      Co-Chairs: H.L. Bonkovsky, MD & G. Ferreira, PhD
      1:00 PM  -  1:35 PM
      ALA or PBG: Which is the Culprit
      Speakers:
      1:35 PM  -  2:10 PM
      Murine Models of Porphyria
      2:10 PM  -  2:45 PM
      Heme Transport and Recycling
      Speakers:
      2:45 PM  -  3:20 PM
      Biochemically Proven Porphyria but No Heme Biosynthetic Gene Mutation– What’s the Defect?
      3:45 PM  -  4:20 PM
      Heme Gazing: Illuminating Heme Trafficking, Dynamics, and Signaling with Fluorescent Heme Sensors
      Speakers:
      4:20 PM  -  4:35 PM
      Selected Abstract 3
      4:35 PM  -  4:50 PM
      Selected Abstract 4
      4:50 PM  -  5:50 PM
      Expert Panel: Critical Issues to Resolve and Future Directions
      Moderators: H.L. Bonkovsky, MD & G. Ferreira, PhD
      Panelists include:
      7:00 PM  -  8:00 PM
      Poster Session
      8:00 PM  -  10:00 PM
      Dinner
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