The Stanford Cancer Center, an NCI-designated center draws upon the expertise of more than 300 researchers and clinicians, and is at the forefront of today’s advances in cancer research and medicine. Stanford scientists and physicians have led the way in developing many of the current state-of-the-art radiology, antibody and biologic therapies that are used to treat cancers.
The Cancer Biology Program is focused on investigating the mechanisms and signaling pathways involved in the development and progression of cancer. The goals are to advance basic understanding of cancer pathogenesis and to facilitate the translation of basic science discoveries into the clinical arena in order to improve the outcomes of patients with cancer.
Program researchers focus on three major scientific themes:
Mechanisms and Pathways of Oncogenesis. Studying the roles of oncogenes and tumor suppressor genes, as well as cell division regulation, genomic stability and DNA damage and repair processes.
Epigenetics. Investigating the causes and impacts of epigenetic (genetic changes caused by external factors) alteration that are increasingly associated with cancer.
Epithelial Neoplasia. Analyzing the molecular and cellular biology of solid tumors through use of a variety of in vitro and in vivo model systems.
The Radiation Biology Program is focused on increasing the effectiveness of radiotherapy for both local tumor control and the survival outcomes of cancer patients.
Program members investigate new ways to enhance the efficacy of radiotherapy by targeting the tumor microenvironment, protecting normal tissue from radiation toxicity, and developing new technology to deliver radiation in a focused manner at high speed. To achieve these goals, basic discovery science, high throughput screening and preclinical models are used to obtain critical supporting data to take these approaches into clinical trials. Thus, the program includes both basic and translational science.
Program research is focused on developing pharmacologic and biologic agents to combine with radiotherapy to improve local tumor control and prevent metastatic spread.
The Cancer Stem Cell Research Program
postulates that self-renewal is a critical function of both cancer stem cells and their normal counterparts and that self-renewal pathways may be co-opted in the process of oncogenesis to support tumor growth.
Based on these concepts, the overall goal of the Program is to identify and characterize self-renewal pathways in model systems, normal tissues and solid tumors. These efforts require the strong integration of basic research with preclinical studies within the program, as well as collaboration with clinical investigators in other programs.
The goal of the Cancer Imaging and Early Detection Program is to advance cancer research, early cancer detection and cancer management by carrying out novel research using multimodality anatomical and molecular imaging strategies and in vitro diagnostics. This goal will be achieved through the development and application of multimodality imaging strategies to reveal the molecular basis of cancer, to develop multiparametric diagnostic tools and to advance the effective treatment for cancer.
The program is comprised of investigators from eight specialty areas:
In vitro diagnostics
Mouse models/small animal imaging applications in cancer therapy
The Immuniogy Program's two major goals are:
To understand the nature of the immune system and its response to malignancies.
To explore auto- and allo-immune responses to cancer with the goal of enabling the discovery and development of more effective anti-tumor immunotherapy.
These goals will be achieved by fostering collaborative research, advancing the latest technologies to probe immunological mechanisms, and by enhancing the infrastructure for clinical translation.
Animal Modeling, Cancer Research, Cancer Therapy, Cell Signaling, Clinical Research, Epigenetics, Genomic Research, High throughput screening, Immunology, Immunotherapy, In vitro diagnostics, In vivo & In vitro modelling, Molecular Imaging, Pharmacology.
Areas of Interest
Antibodies, Cell Culture, Cell Separation/Magnetic Beads, ChIP/MeDIP, Cloning/Ligation, DNA Purification, DNA Sequencing, Electrophoresis, Electroporation, ELISA, Enzymes/Reagents, Flow Cytometry, Genotyping, HPLC/LCMS Columns, Micro RNA, Microarray, Next Gen Sequencing, PCR, Peptides, Pipettors/Tips, Plasticware/Glassware, Primary Cells, Protein Expression, Protein Purification, QPCR/RTPCR, Recombinant Proteins, RNA Purification, Sample Storage and ID, SiRNA/RNAi, Transfection, Western Blot
Seeking ServicescDNA Library construction, Cell Line & Assay Dev., Cloning and Custom vectors, Custom Biochemicals, Custom Cell Cuture media, Custom Cell Isolation, Custom Organic Synthesis, DNA Sequencing, Drug Screening and Profiling, Fluorescent labeling, Gene Synthesis, Genomic Services, Genotyping, In-Vivo Research, Knockout/Knockin/Transgenic mice, Micro RNA Profiling, Oligo Synthesis, Peptide Synthesis, Pipette Repair/Calibration, Protein Production, RNAi validation /miRNA profiling, SNP Detection, Viral Vector Services
Friday, January 27, 2017 12:00 PM - 2:00 PMPacific Time
Stanford UniversityCancer Center & Neuroscience1050 Arastradero RoadPalo Alto, California 94304-5591
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